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Bryce Allred Dec. 6 th 2010. Pushing Brachytherapy one step Further. Brachytherapy Methods. Brachytherapy Isotopes. 1910- urethral radium 1601 yr half life 1922- many complications Au-198 γ-ray of .412 MeV Half life of 2.7 days I-125 .027 MeV γ rays 60 day half life. α/β Ratios.
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Bryce Allred Dec. 6th 2010 Pushing Brachytherapy one step Further
Brachytherapy Isotopes • 1910- urethral radium • 1601 yr half life • 1922- many complications • Au-198 • γ-ray of .412 MeV • Half life of 2.7 days • I-125 • .027 MeV γ rays • 60 day half life
α/β Ratios • -N*(α*D+β*D^2) • S= e • α is the linear term dealing with double strand break • β Is the quadratic term dealing with single strand break
New Isotopes • Palladium-103 has proven to be very effective • External beam therapy is currently compensating for lack of brachytherapy
Electrons travel finite distance • A photons probability of attenuation makes it unsafe • Electrons can treat an organ without harming other organs
Choosing Isotope • Needs similarly even distribution • Energy of around 5 MeV and a half life between 10 and 40 days
May prove to be very effective in isolating treatment. Computer simulations and phantom readings will be used to perform research Conclusion