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Technology Advances

Technology Advances. Mark Fornalik & Brian Aylward. Technical Prowess & Innovation. Our historical success has been based on the design and manufacture of precision, multi-layered films consisting of high-performance, engineered materials with unique physical and chemical properties.

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Technology Advances

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  1. Technology Advances Mark Fornalik & Brian Aylward

  2. Technical Prowess & Innovation Our historical success has been based on the design and manufacture of precision, multi-layered films consisting of high-performance, engineered materials with unique physical and chemical properties Small Particle Manufacturing

  3. Knowledge of all three factors is needed to design effective products Ag Antimicrobials Technology Effectiveness of any Ag AM will depend on three factors: 1. Ag form (solubility, chemistry, size, etc.) 2. Delivery vehicle (polymer permeability, Ag release rate, surface properties, etc.) 3. Microbial environment (water content, pH, ionic nature/strength, viscosity, flow, etc.)

  4. Gram Negative Bacteria Gram Positive Bacteria P O O L P TA P SH Ribosom Protein NH2 RNA DNA A Mycobacteria M Ag+/Cell Interaction TA Yeast PM O MP.G.C. P CM G • Most biocides only impact one cellular function • Silver can disrupt cell growth by multiple means

  5. Gram Negative Bacteria Gram Positive Bacteria P O O L P TA P SH Ribosom Protein NH2 RNA DNA A Mycobacteria M Ag+/Cell Interaction TA Yeast PM O MP.G.C. P CM G • Most biocides only impact one cellular function • Silver can disrupt cell growth by multiple means • Modification of Plasma Membrane

  6. Gram Negative Bacteria Gram Positive Bacteria P O O L P TA P SH Protein NH2 A Mycobacteria M Ag+/Cell Interaction TA Ribosom Yeast RNA PM O DNA MP.G.C. P CM G • Most biocides only impact one cellular function • Silver can disrupt cell growth by multiple means • Interferes with DNA and RNA functionality

  7. Gram Negative Bacteria Gram Positive Bacteria P O O L P TA P Ribosom RNA DNA A Mycobacteria M Ag+/Cell Interaction TA SH Protein NH2 Yeast PM O MP.G.C. P CM G • Most biocides only impact one cellular function • Silver can disrupt cell growth by multiple means • Blocking of Thiol groups on proteins and enzymes

  8. biostatic Ag+ Ag+ Ag+ biocidal Ag+ Ag+ Stopping Biogrowth Ag+ Ag+ planktonic Ag+ Ag+ Ag+ Ag+ Killing Microbes Biocides, Biostats & Biofilms

  9. Old Generation Ag-Antimicrobial Silpure Ag-Antimicrobial Surface Concentration of Microbial Species With Time Surface Concentration of Microbial Species With Time Antimicrobial Contamination (colony forming units) Antimicrobial Contamination (colony forming units) Time Time Surface Concentration of Silver Species With Time Surface Concentration of Silver Species With Time Surface concentration of silver species Surface concentration of silver species Time Time

  10. Silpure Formulation • Active • Specially formulated silver chemistry for controlled ion release in microbial environment (textiles) • Manufactured to specific particle size, shape and morphology for optimal surface coverage and antimicrobial efficacy

  11. Silpure Formulation… • Binder System • Polymeric binder system to provide adhesion of silver to fabric materials • Co developed with silver technology to provide additional control of ion release for long lasting antimicrobial efficacy • Designed for optimal performance in padding processes • Compatible with a wide range of textile auxiliaries

  12. Untreated Fabric- A Closer Look

  13. Treated Fabric • Topically adhered • Uniform Coverage • Maximum Durability

  14. Product Information • Target application will be 1-3% (performance dependent) • Active (silver) concentration in blended product will be 0.24% • Final goods will therefore contain between 0.0024 and 0.0072% active (24-72 ppm)

  15. Silpure FBR-5 Performance Evaluation • Eliminates bacteria growth • Highly durable antimicrobial performance

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