1. Human Frontier Science Program The Human Frontier Science Program promotes international collaborations on the mechanisms underlying the complex functions of living systems. HFSP supported research must be novel, interdisciplinary, and intercontinental.

2. Member Supporting Parties G7 CountriesCanada , France , Germany , Italy, Japan, UK, USA Switzerland European Union (through European Commission) Austria, Belgium, Denmark, Finland, Greece, Luxembourg, the Netherlands, Portugal,the Republic of Ireland, Spain, Sweden

3. Areas of Research Support Research into the mechanisms underlying the complex functions of living organisms ranging from biological functions at the molecular level to higher brain functions.

4. Scientific Programs • Research Grants: for international teams of scientist embarking on novel interdisciplinary research. Program Grants Young Investigators • Long-term Fellowships: for postdoctoral training in another country; third year of support can be used for repatriation • Career Development Award: funding to support independent research in home country by former LTF • Short-term Fellowships: short visit to establish new collaborations • Annual Awardee Meetings

5. New Developments- opportunities for young scientists - • Long-Term Fellowships:- 3 years with possibility of repatriation- Career Development Award – independent research support for fellows returning to their home countries • Research Grants • special program for Young Investigators • introduction of two step review procedure with letter of intent

6. Nationality Eligibility Criteria • Long-Term Fellowships: • Nationals of Member Supporting Countries can undertake a fellowship in any country with the exception of their home country or country in which they performed/received their doctoral degree • Nationals of other countries must undertake a fellowship in one of the Member Supporting Countries • Fellowships cannot be used to move from one laboratory to another in the same country • Research Grants • There are no restrictions on the nationality for team members, however the Principal Investigator must be from a Member Supporting Country.

7. Research Grants • For novel, innovative, interdisciplinary approaches to basic biological research • International , especially intercontinental collaboration • Involvement of other disciplines such as chemistry, physics, mathematics, computer science and engineering

8. Human Frontier Science Program • International, intercontinental research collaboration in the field of basic biology • Original, challenging ideas are most welcomed • Researchers early in their careers are strongly encouraged to apply • Preliminary results are not required • Pioneering journeys into uncharted scientific territories: greater potential rewards of “science”

9. Young Investigator Grants • 3 years at $250,000 per year • Within 5 years of obtaining an independent position • Not more than 10 years after PhD

10. Program Grants • for scientists at any stage of their careers • team members are expected to embark upon new projects • 3 years up to $500,000 per year

11. Research GrantsApplication procedure • Submission of Letter of Intent by March 30, 2001 • Electronic submission via web site • Selected invitations for full applications (Deadline September 2001, for awards March 2002)

12. Research Grant Holders Country Distribution 1990-2001

13. Intercontinental Collaboration • International, especially intercontinental collaboration • 80% of HFSP-funded research grants from 1990 to 2000 involved intercontinentalcollaborations

14. Research Grants 2001 Young Investigators Program Grants 85 applications / 12 awardsNeuroscience: 28 appl. / 6 awards Molecular: 57 appl. / 6 awards 301 applications / 41awardsNeuroscience: 99 appl. / 12 awards Molecular: 202 appl. / 29 awards

15. HUMAN FRONTIER SCIENCE PROGRAMRESEARCH GRANTS ITALIAN PARTICIPATION ON RESEARCH GRANTS (1990-2001) Italians Other Nationalities Researchers 52 4 In Italy Researchers 38 - Outside Italy

16. Long-term Fellowships • Goal: To enable scientists within 3 years of completing their Ph.D. to obtain postdoctoral training abroad • Tenure up to 3 years • 3rd year can be used for repatriation to home country and can be deferred for up to two years • Repatriating Long-term Fellows are eligible for an HFSP Career Development Award

17. HUMAN FRONTIER SCIENCE PROGRAMLONG TERM FELLOWS 1990-2001 (1630 LTF)

18. HUMAN FRONTIER SCIENCE PROGRAM ITALIAN HFSP LONG-TERM FELLOWS HFSP FELLOWS 1990-2001  FEMALE MALE TOTAL 20 42 62

19. HUMAN FRONTIER SCIENCE PROGRAM ITALIAN HFSP LONG-TERM FELLOWS Host Country Number CANADA 2 FRANCE 4 GERMANY 6 SWITZERLAND 5 THE NETHERLANDS 1 UK 6 USA 38 TOTAL 62

20. HUMAN FRONTIER SCIENCE PROGRAMLONG-TERM FELLOWSHIPS STATUS OF FORMER ITALIAN HFSP FELLOWS* TOTAL 48 Returned to Italy 20 Remained in Host Country 21 Moved to Another Country 7 *Having completed their fellowships before 11/02/2002

21. Career Development Award • Goal: To enable young investigators to develop independent research programs upon returning to their home country: • Provides $90,000 per year for 2 years for salary and research support for former HFSP fellows. Funding can be extended to 3 years at $60,000 per year. • Fellows must have returned to their home country and be appointed to a position allowing them to perform independent research • Program will start at the earliest in 2003

22. Short-term Fellowships • Goal: to enable scientists to establish new collaborations or to learn new techniques • Provides travel and per diem for periods of 2 weeks to 3 months in a laboratory in a foreign country • For scientists at all stages of their careers to spend time in a new laboratory • For former HFSP Long-term Fellows to visit their former host laboratories

23. HUMAN FRONTIER SCIENCE PROGRAMINFORMATION http://www.hfsp.org SECRETARY GENERAL: TORSTEN WIESEL DEPUTY SEC. GENERAL TAKAYUKI SHIRAO DIRECTOR OF FELLOWSHIPS: DANUTA KROTOSKI RESEARCH GRANT DIRECTORS:MARTIN REDDINGTON TAKASHI SHIMIZU FINANCE AND ADMINISTRATION DIRECTOR PATRICK VINCENT