1 / 1

Targeted Transactivation of Mouse BMPRII Gene with Conditional Deletion in Smooth Muscle Cells

This study focuses on a genetically manipulated mouse model where the BMPRII gene is conditionally deleted in smooth muscle cells using a transactivator system. The system involves the regulation of BMPRII expression through genetic modification using floxed regions, transactivator proteins, and inducible elements. The model allows for precise manipulation of BMPRII expression in a specific cellular context, providing insights into its role in smooth muscle function.

alize
Télécharger la présentation

Targeted Transactivation of Mouse BMPRII Gene with Conditional Deletion in Smooth Muscle Cells

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Target Transactivator X Mouse with Floxed BMPRII TRE-PminCMV CRE SM 22a tTA SM22-tTA+/Cre+ CRE CRE TRE-PminCMV TRE-PminCMV tTA SM 22a exon 4 exon 5 Frt LoxP LoxP SM 22a tTA Doxycycline Frt LoxP Mouse with conditionally deleted BMPRII in SMC X

More Related