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anti c3 antibody

Mouse anti Human C3a antibody, clone H13 recognizes human C3a anaphylatoxin, a cleavage product of human complement component C3.<br>https://www.creative-diagnostics.com/Anti-C3-Mab-234619-144.htm<br>

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anti c3 antibody

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  1. Anti-C3 monoclonal antibody, clone H13 (CABT- Anti-C3 monoclonal antibody, clone H13 (CABT- 45010MH) 45010MH) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Product Overview Product Overview Mouse anti Human C3a antibody, clone H13 recognizes human C3a anaphylatoxin, a cleavage product of human complement component C3. C3a increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Mouse anti Human C3a antibody, clone H13 recognizes a C3a-determinant also present on native C3. Clone H13 allows discrimination of ubiquitous or non-specifically bound native C3 or C3a from biologically active C3b fragment, neither C3b or C5 components are recognized by clone H13. Mouse anti Human C3a antibody, clone H13 is reported to block C3a functional activity. Specificity Specificity C3 Immunogen Immunogen Human complement component C3. Isotype Isotype IgG2b Source/Host Source/Host Mouse Species Reactivity Species Reactivity Human, Guinea pig, Rabbit Clone Clone H13 Conjugate Conjugate Unconjugated Applications Applications IHC-Fr; ELISA; WB Format Format Purified IgG - lyophilised Size Size 50 μg Preservative Preservative 0.09% Sodium Azide, 0.5% Bovine Serum Albumin. Storage Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Warnings Warnings For research purposes only 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved

  2. GENE INFORMATION GENE INFORMATION Gene Name Gene Name C3 complement component 3 [ Homo sapiens (human) ] Official Symbol Official Symbol C3 Synonyms Synonyms C3; complement component 3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; complement C3; prepro-C3; C3a anaphylatoxin; complement component C3; complement component C3a; complement component C3b; acylation-stimulating protein cleavage product; epididymi Entrez Gene ID Entrez Gene ID 718 mRNA Refseq mRNA Refseq NM_000064 Protein Refseq Protein Refseq NP_000055 MIM MIM 120700 UniProt ID UniProt ID P01024 Chromosome Location Chromosome Location 19p13.3-p13.2 Pathway Pathway Activation of C3 and C5; Adaptive Immune System; Alternative complement activation; Chagas disease (American trypanosomiasis); Class A/1 (Rhodopsin-like receptors); Complement Activation, Classical Pathway; Complement and Coagulation Cascades; Complement and coagulation cascades; Function Function C5L2 anaphylatoxin chemotactic receptor binding; endopeptidase inhibitor activity; protein binding; receptor binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved

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