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120. 100. 80. Viable cells (% of control). 60. pH 6 .0. 40. pH 7 .0. 20. pH 8 .0. 0. 0.01. 0.1. 1. 10. C oncentration of NaHS ( mM). Supplemental Fig. 1. 120000. 100000. 80000. Chemiluminescent intensity ( arbitrary units). 60000. 40000. 20000. 0. NaHS. Control.

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  1. 120 100 80 Viable cells (% of control) 60 pH6.0 40 pH7.0 20 pH8.0 0 0.01 0.1 1 10 • Concentration of NaHS (mM) Supplemental Fig. 1

  2. 120000 100000 80000 Chemiluminescent intensity (arbitrary units) 60000 40000 20000 0 NaHS Control NaHS+Z-VAD NaHS+Z-VDVAD Supplemental Fig. 2

  3. 50000 * * 40000 30000 * Chemiluminescent intensity (arbitrary units) 20000 10000 0 • NaHS+ • Nocodazole NaHS Cont • NaHS+ • CytochalasinD Supplemental Fig. 3

  4. Cont NaHS NaHS+Cytochalasin D ROCK1 Cleaved ROCK1 Cleaved ROCK2 Tubulin ROCK2 Tubulin Supplemental Fig. 4

  5. 120000 * * 100000 80000 Chemiluminescent intensity (arbitrary units) 60000 40000 20000 0 Control NaHS + Y27632 NaHS Supplemental Fig. 5

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