Supplementary Fig. 2

S.enterica MNTSELETLIRTILSEQLTTPAQTPVQ--------PQGKGIFQSVSEAIDAAHQAFLRYQ 52 K.pneumoniae MNTAELETLIRTILSEKLAPTPPAPQQ--------EQG--IFCDVGSAIDAAHQAFLRYQ 50 L.reuteri MQINDIESAVRKILAEELD-NASSSSANVAATTDNGHRG-IFTNVNDAIAAAKAAQEIYR 58 L.collinoides MADQNIEAEIRRILQEELSGNASSSAAGTTTSQPDGLGNRIFTNVNDAIAAAKQAQAIYQ 60 * ::*: :* ** *:* . :. ** .*..** **: * *: S.enterica QCPLKTRSAIISAMRQELTPLLAPLAEESANETGMGNKEDKFLKNKAALDNTPGVEDLTT 112 K.pneumoniae QCPLKTRSAIISALRETLAPELATLAEESATETGMGNKEDKYLKNKAALENTPGIEDLTT 110 L.reuteri DKPIAVRQQVIDAIKEGFRPYIEKMAKDIKEETGMGTVEAKIAKLNNALYNTPGPEILEP 118 L.collinoides DKPLAFRKKVVQAIKDGFGPYIEYMAKQTREETGMGTAEAKIAKLKNALYNTPGVELLDP 120 : *: *. ::.*::: : * : :*:: *****. * * * : ** **** * * . S.enterica TALTGDGGMVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIYFSPHPGAKKVSL 172 K.pneumoniae SALTGDGGMVLFEYSPFGVIGAVAPSTNPTETIINNSISMLAAGNSVYFSPHPGAKKVSL 170 L.reuteri VVENGDGGMVMYERLPYGVIGAVGPSTNPSETVIANAIMMLAGGNTLYFGAHPGAKNVTR 178 L.collinoides EVETGDGGMVMYEYTPFGVIGAVGPSTNPCETVLNNSIMMMSAGNALFFGAHPGAKNITR 180 . .******::* *:****:*.***** **:: *:* *::.**:::*..*****::: S.enterica KLISLIEEIAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAITGGPGIVAMGMKSGK 232 K.pneumoniae KLIARIEEIAYRCSGIRNLVVTVAEPTFEATQQMMSHPLIAVLAITGGPGIVAMGMKSGK 230 L.reuteri WTIEKMNDFIADATGLHNLVVSIETPTIESVQQMMKHPDIAMLAVTGGPAVVHQAMTSGK 238 L.collinoides WAVEKLNEFVYKATGLKNLLVSLDTPSIESVQEMMQHPDVAMLAVTGGPAVVHQALTSGK 240 : :::: . *::**:*:: *::*:.*:** ** :*:**:****.:* .:.*** S.enterica KVIGAGAGNPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKSLIVVESVAERLVQQMQ 292 K.pneumoniae KVIGAGAGNPPCIVDETADLVKAAEDIISGAAFDYNLPCIAEKSLIVVASVADRLIQQMQ 290 L.reuteri KAVGAGPGNPPAMVDATADIDLAAHNIITSASFDNDILCTAEKEVVAESSIKDELIRKMQ 298 L.collinoides KAVGAGAGNPPAMVDATADIDLAAHNLFTSAKFDNEILCTSEKEIIAEDSIKDELLQKIV 300 *.:***.****.:** ***: **.:::..* ** :: * :**.::. *: :.*:::: S.enterica TFGALLLSP-ADTDKLRAVCLPE-GQANKKLVGKSPSAMLEAAGIAVPAKAPRLLIALVN 350 K.pneumoniae DFDALLLSR-QEADTLRAVCLPD-GAANKKLVGKSPAALLAAAGLAVPPRPPRLLIAEVE 348 L.reuteri DEGAFVVNR-EQADKLADMCIQENGAPDRKFVGKDATYILDQANIPYTGH-PVEIICELP 356 L.collinoides AKGACLVTDPKDIKHLADMTIGDNGAPDRKYVGKDATVILDAAGISYTGD-PKLIMMDVD 359 .* ::. : . * : : : * .::* ***..: :* *.:. . * :: : S.enterica ADDPWVTSEQLMPMLPVVKVSDFDSALALALKVEEGLHHTAIMHSQNVSRLNLAARTLQT 410 K.pneumoniae ANDPWVTCEQLMPVLPIVRVADFDSALALALRVEEGLHHTAIMHSQNVSRLNLAARTLQT 408 L.reuteri KEHPLVMTEMLMPILPVVSCPTFDDVLKTAVEVEKGNHHTATIHSNNLKHINNAAHRMQC 416 L.collinoides KDNPLVKTEMLMPILPIVGCPDFDAVLATAIEVEGGNHHTASIHSNNILHINKAAHRMNT 419 :.* * * ***:**:* . ** .* *:.** * **** :**:*: ::* **: :: S.enterica SIFVKNGPSYAGIGVGGEGFTT----FTIATPTGEGTTSARTFARSRRCVLTNGFSIR-- 464 K.pneumoniae SIFVKNGPSYAGIGVGGEGFTT----FTIATPTGEGTTSARTFARLRRCVLTNGFSIR-- 462 L.reuteri SIFVVNGPSYVGTGVADNGAHSGASALTIATPTGEGTCTARTFTRRVRLNSPQGFSVRNW 476 L.collinoides SIFVANGPTFAATGVGDNGYYSGAAALTIATPTGEGTTTTKTFTRRRRFNCPQGFSLRSW 479 **** ***::.. **..:* : :********** :::**:* * .:***:* S.enterica -- K.pneumoniae -- L.reuteri Y- 477 L.collinoides EV 481 Supplementary Fig. 2

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