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Supplementary Fig. 1 PowerPoint Presentation
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Supplementary Fig. 1

Supplementary Fig. 1

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Supplementary Fig. 1

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  1. Supplementary Fig. 1 NCI/ADR-RES OVCAR-8 DXR 4μM SM: - + - + - + PTEN p53 p130Cas β-actin

  2. Supplementary Fig. 2 4μM SM: mock CA-Stat3 – + – + p-Stat3 p-Stat3/actin: Stat3 Cyclin D1 cyclinD1/actin: Skp2 Skp2/actin: p27Kip1 p27Kip1/actin: β-actin

  3. Supplementary Fig. 3 SM (μM) : 0 1 2 4 EGF SM (μM) : 0 1 2 4 A B p-Stat3 (Y705) p-EGFR (Y1068) Stat3 EGFR β-actin p-JAK2 (Y1007/1008) JAK2 β-actin

  4. Supplementary Fig. 4 * A B NCI/ADR-RES OVCAR-8 NCI/ADR-RES DXR OVCAR-8 DXR 4μM SM: - + - + - + 4μM SM: - + - + - + OVCAR-8 MDR-1 MDR-1 24hr β-actin β-actin MDR-1 72hr D β-actin NCI/ADR-RES C Cont DMSO 4μM SM DXR Rhodamin123 accumulation

  5. Supplementary Fig. 5 OVCAR-8 DXR 4μM SM: - + - + c-myc β-actin

  6. Supplementary Fig. 6 OVCAR-8 DXR 24 48 72 24 48 72 (hr) 4μM SM: - + - + - + - + - + - + Skp2 p-Akt (S473) Akt β-actin

  7. Supplementary Fig. 7 NCI/ADR-RES OVCAR-8 DXR 4μM SM: - + - + - + β-catenin β-actin