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Path Analysis

Path Analysis. Research questions. Is SNP rs10879357 associated with CWP? How are depression and/or sleep problems involved in this relationship?. Step 1 – SNP associated with CWP?. 1.8. SNP. CWP. Step 2 – is this association independent of depression?. 1.6. SNP. CWP. 1.4. Depression.

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Path Analysis

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  1. Path Analysis

  2. Research questions • Is SNP rs10879357 associated with CWP? • How are depression and/or sleep problems involved in this relationship?

  3. Step 1 – SNP associated with CWP?

  4. 1.8 SNP CWP

  5. Step 2 – is this association independent of depression?

  6. 1.6 SNP CWP 1.4 Depression

  7. Step 3 – is the SNP associated with depression?

  8. 1.6 SNP CWP 1.02 1.4 Depression

  9. Sleep problems?

  10. 1.7 SNP CWP 1.3 Sleep problems

  11. Step 3 – is the SNP associated with sleep problems?

  12. 1.7 SNP CWP 1.3 1.01 Sleep problems

  13. Path model SNP Depression CWP Sleep problems

  14. Path model – in STATA • pathreg command • models each potential pathway

  15. Path model 0.08 0.04 0.19 SNP Depression CWP 0.05 r2=0.53 0.56 0.48 Sleep problems 0.999 0.827 0.783

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