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This study explores the expression of the ZNF313 gene in various tissues, including the cerebellar lobe, during different developmental stages (embryonic day 18, postnatal days 7 and 30). We analyze its expression in both normal and cancerous samples, including breast cancer cell lines (HCC1937, MCF7, etc.) and normal tissues like bladder and liver. The findings aim to elucidate the role of ZNF313 in cerebellar development and its potential implications in cancer biology. Supplementary materials include graphical data representation and comparative analysis.
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Control ZNF313 p21WAF1 Intermediate deep cerebellar nucleus Embryonic day 18 Postnatal day 7 Postnatal day 30 Cerebellar lobe Cerebellar lobe Purkinje cell layer Postnatal day 30 Lateral vestibular nucleus Postnatal day 30 Normal Breast BT20 HCC1937 HS578T MCF7 MDA-MB231 MDA-MB453 MDA-MB468 SK-BR-3 T47D ZR-75-1 ZNF313 GAPDH Normal bladder T24 HT1197 HT1376 253J 253J-BV Normal liver Hep3B HepG2 ZNF313 GAPDH Supplementary Fig. S7 a b