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This supplementary figure presents a detailed microarray analysis examining the transcriptional regulation of ten genes from the Rac-GAP family by Hepatocyte Growth Factor (HGF) at different time points: 1 hour, 6 hours, and 24 hours. Key genes analyzed include ArhGAP1, ArhGAP5, and ArhGAP12, among others. The data is expressed in Log2 ratio format, providing insights into the temporal dynamics of gene expression regulation by HGF. This analysis is essential for understanding the molecular mechanisms underlying HGF's role in cell signaling and function.
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HGF 1h HGF 6h HGF 24h 1 0.5 0 -0.5 -1 -1.5 -2 -2.5 -3 Abr Bcr Chn2 Sh3bp1 Arhgap5 Arhgap9 Arhgap1 Racgap1 Arhgap29 Arhgap12 Log2 Ratio Gentile et al., Supplementary Figure 4 Microarray analysis of the transcriptional regulation by HGF at different times of ten genes of the Rac-GAP family, including ArhGAP12.