Impact of PDPN Expression Levels on Cellular Proportions in Tumor Microenvironment

Jan 01, 2026

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Supplementary Figure 2 illustrates the cellular distribution of PDPN-positive and PDPN-negative cells within the tumor microenvironment. The analysis shows that PDPN+ cells constitute 90.8% of the total population, while cancer-associated fibroblasts (CAFs) represent 4.37% with lower PDPN expression. In stark contrast, PDPN- cells make up only 0.44%. These findings highlight the significant role of PDPN in shaping cellular dynamics in tumors, emphasizing its potential as a marker for therapeutic targeting.

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Impact of PDPN Expression Levels on Cellular Proportions in Tumor Microenvironment

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