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Enhancing T Cell Responses with CTB Fusion in HIV-1 Derived Antigen DNA Vaccines

Separating TRIVN and CTB into two DNA vaccines reduced the genetic adjuvant effect on specific T cell responses elicited by HIV-1 antigen. Integrating CTB with TRIVN showed improved T cell responses.

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Enhancing T Cell Responses with CTB Fusion in HIV-1 Derived Antigen DNA Vaccines

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  1. Supplementary figure 1 The fusion expressed CTB could improve specific T cell responses elicited by TRIVN (Tat, Rev, Integrase, Vifand Nef fusion antigen derived from HIV-1). However, when separating TRIVN and CTB into two DNA vaccines, the genetic adjuvant effect decreased.

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