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Understanding Blood Group Genetics: MNSs and Kell System Variants

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  1. Other Blood Groups

  2. S+ s+ S+ s- S- s+ S- s- MNSs • M+ N+ • M+ N- • M- N+ • M- N-

  3. MNSs • MNSs Chromosome 4 • Ns>Ms>MS>NS • MNSs Co dominant

  4. MNSs • S 29 Met • s 29 Ter • Milten berger Hybridof A,B, E glycophorin

  5. MN A IgM • SsB IgG

  6. M + Band 3 Wrb

  7. Antibody • Vicia Graminia Anti N • Ibris Amara Anti M

  8. Lewis

  9. Product of Lewis • Lewis Chromosome19 Fut3 • Se Chromosome19 Fut2 • GI Cells GI Blood RBC

  10. Lewis recipient of H.Pylori • Lewis Null Recurrent Candida

  11. Kell • Kell Chromosome 7 • Allels: K / k Kpa /Kpb Jsa/Jsb • Inheritance: Codominant . Protein: fusion with Kx protein Kx null Mc Load phenotype

  12. Kell CGD Corea Muscular Dystrophy

  13. اعتماد بنفس

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