1 / 19

Human Genome Project, Gene Therapy, and Cloning

Human Genome Project, Gene Therapy, and Cloning . Adapted from the University of Utah Genetic Science Learning Center and The National Genome Research Institute, National Institutes of Health. The Human Genome Project. An international effort to decipher the DNA blueprint of a human being.

quincy-greer
Télécharger la présentation

Human Genome Project, Gene Therapy, and Cloning

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Human Genome Project, Gene Therapy, and Cloning Adapted from the University of Utah Genetic Science Learning Center and The National Genome Research Institute, National Institutes of Health

  2. The Human Genome Project • An international effort to decipher the DNA blueprint of a human being

  3. Human Genome Project Goals: • To sequence & determine the exact order of the nucleotides (A,C,T,G) for ALL of the DNA in a human cell • To determine which sections of DNA represent the individual genes • To store this information in databases for analysis

  4. Publishing the human genome

  5. How genes influence an individual’s response to drugs

  6. Gene Therapy Replacement of an abnormal protein with a normal one • Isolate the normal sequence for a gene and package it into a virus (vector). • Infect a target cell, usually the one with the illness, such as a liver or lung cell. • The cell uses the normal sequence to produce the missing protein and is thus repaired.

  7. Problems with Gene Therapy • Short lived, so patients have to go through multiple rounds • Immune response to foreign invaders • Problems with the viruses • Very expensive • Multigene disorders:disorders like heart disease, high blood pressure, Alzheimer’s disease, diabetes are caused by the combined effects of variations in many diseases.

  8. What is Cloning? • Cloning is the creation of an organism that is the EXACT genetic copy of the mother • Identical twins are natural clones, they share 100% of their DNA

  9. How do you clone an organism? • Remove the nucleus from an egg cell and a regular cell from a donor. • Fuse the enucleated cell with a regular cell (that still has its nucleus) by electric shock • The new fused cell begins dividing, just as a fertilized egg would. • The embryo is placed in the uterus of a surrogate mother and allowed to develop normally. • The surrogate mother gives birth to a genetic clone of the original egg cell donor donor!

More Related