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Understanding the Role of TGF-beta in UUO-Induced Kidney Fibrosis

This study investigates CTGF and TGF-beta expression levels in UUO-induced kidney fibrosis in rats, highlighting their role in disease progression. The results suggest a significant fold increase in gene expression compared to the control group.

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Understanding the Role of TGF-beta in UUO-Induced Kidney Fibrosis

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  1. CTGF TGFß 7 7 * 6 6 * * * 5 5 * 4 * 4 # fold increase/18S fold increase/18S 3 3 2 2 1 1 0 0 UUO 8d +B1Ra UUO 8d +B1Ra Sham UUO 3d Sham UUO 8d UUO 3d UUO 8d CCL2 CCL7 * * 60 100 * * # 40 * # fold increase/18S 50 fold increase/18S * 20 0 0 UUO 8d +B1Ra UUO 8d +B1Ra Sham Sham UUO 8d UUO 3d UUO 8d UUO 3d

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