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Supplementary figure 1

Control (DMSO). LY294002 (20 M). Supplementary figure 1. B. A. OCUM -2M. OCUM - 2MD3. OCUM-2M. OCUM-2MD3. 0. 5. 0. 5. min. p85. P-Akt. Actin. Akt. Supplementary figure 2. B. A. : Control. : PP2 0.5 M. 4. : PP2 2 M. : PP2 5 M. 50. : PP2 10 M. 3. 40. *. *. *.

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Supplementary figure 1

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  1. Control (DMSO) LY294002 (20 M) Supplementary figure 1

  2. B A OCUM -2M OCUM - 2MD3 OCUM-2M OCUM-2MD3 0 5 0 5 min p85 P-Akt Actin Akt Supplementary figure 2

  3. B A : Control : PP2 0.5M 4 : PP2 2M : PP2 5M 50 : PP2 10M 3 40 * * * 30 %binding 2 20 10 1 0 1 5 25 (M) Control PP2 12 48 72 (hour) 24 Supplementary figure 3

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