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This guide explores the intricacies of the cell cycle, highlighting key reproductive processes including asexual reproduction, where a single organism produces genetically identical clones, and sexual reproduction, involving two parents and resulting in genetic diversity. The phases of the cell cycle—interphase and mitosis—are explained in detail, covering G1, S, and G2 stages, followed by mitotic phases: prophase, metaphase, anaphase, and telophase. Insights into cytokinesis and the control mechanisms that ensure proper cell division are also discussed, important for understanding growth, tissue repair, and cancer implications.
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Reproduction • Asexual Reproduction: • Involves only 1 organism • New individual is genetically identical to parent-clone • Single celled organisms • - binary fission: cell divides in 2
Multicelled organisms: • Budding • Plant propagation • Parthenogenesis
Reproduction • Sexual Reproduction: • Involves 2 parental organisms • New individual is different from either parent • Leads to greater genetic diversity
Chromosome Structure • Chromatin: DNA and protein in long, thin thread-like, invisible form
Chromosome Structure • Chromosomes: Condensed chromatin that appear right before cell division • Sister chromatids- contain exact copies of DNA- • Centromere- protein “button” holds chromatids together
The Cell Cycle • The time it takes from 1 cell division to the next • Varies in length of time depending on cell type
The Cell Cycle • Function -asexual reproduction • Single celled organisms -produce new individuals- • Multicelled organisms – • Growth -increase in size by increasing in cell number • Tissue replacement and repair
The Cell Cycle Two alternating periods • Interphase- growth • Mitosis- division Interphase Growth Division Mitosis
The Cell Cycle Interphase: • The growth period. • Longest phase of the cell cycle • Cell spends 98% of time in interphase • 3 stages
3 Stages of Interphase G1 -1st Gap phase: • The cell growsin size and carries on normal functions S - Synthesis phase: • DNA Replication • Chromosomes copied in preparation for cell division. G2 - 2nd Gap phase: • Structures needed for cell division are assembled. • No turning back- cell division will occur
Phases of the Cell Cycle How the Cell Cycle Works
The Cell Cycle • Mitosis: • The division period • Division of the nucleus • Four distinct phases. • Prophase • Metaphase • Anaphase • Telophase The Cell Cycle
Prophase • First phase of mitosis • Chromatin condenses and chromosomes become visible • Nuclear membrane and nucleoli disappear • Structures necessary for cell division appear • Centrioles- barrel shaped, 2 pair, each moves to opposite poles • Spindle fibers- span the two poles
Metaphase • Chromosomes line up along the midline of the cell
Anaphase • Centromeres and sister chromatids separate • Spindle fibers shorten and pull chromatids, now called chromosomes, toward opposite poles
Telophase • Reverse of Prophase • Begins when chromosomes stop after reaching poles • Chromosomes decondense to less visible chromatin form • Nucleoli reappear • Nuclear membrane appears around each set of chromosomes
Cytokinesis Division of the cytoplasm and organelles Results in 2 daughter cells New cells begin a new cell cycle Different for plants and animals
Animal Cell Cytokinesis • Cleavage furrow-cell membrane pinches in Animation: Mitosis Mitosis
Plant Cell Cytokinesis • Cell plate formation- new cell wall is added to separate 2 daughter cells onion root tip
Control of the Cell Cycle • A series of enzymes monitor a cell’s progress from phase to phase. • A disrupted cell cycle can result in excessive cell division, or cancer
Skin Cancers http://www.skincancer.org/skin-cancer/melanoma/melanoma_2.html