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This study investigates the effect of antisense oligonucleotides (ASO) on phosphorylated tyrosine (pTyr) levels in a high-fat diet (HFD) control group. We examined the relationship between ASO treatment and DEP-1 modulation, utilizing various measurements in arbitrary units. Our findings suggest significant changes in pTyr levels correlated with ASO treatment, indicating potential pathways for DEP-1 regulation in lipid metabolism. Figure S1 provides a comprehensive overview of the experimental results and their implications for further research.
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supporting data A B pTyr 99 HFD control ASO DEP-1 ASO kDa 1.6 170 1.4 130 1.2 100 1.0 70 0.8 arbitrary units pTyr 99 0.6 55 0.4 0.2 40 0 HFD DEP-1 ASO control ASO GAPDH 35 Figure S1