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Mastering NCBI Entrez: Essential Database Search Techniques for Biomedical Literature

This guide provides an overview of how to effectively use NCBI Entrez and its various databases, including PubMed and PMC. Learn search strategies such as utilizing Boolean operators (AND, OR, NOT), wildcard characters, and phrase searching to refine your queries. Gain insights into specialized databases like OMIM and UniGene to enhance your research efficiency. This resource is essential for anyone looking to navigate the vast array of biomedical literature and data available through NCBI.

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Mastering NCBI Entrez: Essential Database Search Techniques for Biomedical Literature

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Presentation Transcript

  1. Exercise 1 Database searches

  2. Tasks of the day • Learn to use NCBI ENTREZ (gquery) • PubMed • Biomedical literature • PMC • PMC is a free full-text archive of biomedical and life sciences journal literature at the • PopSet

  3. Tasks of the day • OMIM • UniGene • Homologene • Entrez Gene

  4. Tips for search in NCBI • Search terms typed in the query box are automatically ANDedi. e. the search engine returns documents that include all of them. • boolean operators: AND OR NOT • Wildcard character * • COX searches only for COX, but COX* searches anything that starts with COX, like COX1A, COX1B etc • Phrase search • “pinussylvestris” rather thanpinussylvestris

  5. Use limits, filters and advanced search builder to create your search

  6. Note • NCBI Entrez and Gquery NCBI Global Cross-database Search • https://www.ncbi.nlm.nih.gov/gquery/gquery.fcgi

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