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This study explores the interaction of C4-HSL and 3-oxo-C12-HSL in different patient isolates. The measurements of these molecules in micromolar concentrations (µM) provide insights into their potential roles in microbial communication and virulence associated with various pathogens. Understanding the dynamics of these signaling molecules could lead to improved therapeutic strategies in managing infections in patients. The analysis focuses on the concentrations present in isolates from 120 to 80 and 60 µM ranges, highlighting their significance in clinical contexts.
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B A 10 1 3-oxo-C12-HSL (µM) C4-HSL (µM) 0.1 1 8 12 13 8 12 13 Patient Patient C 120 100 80 60 C4-HSL / 3-oxo-C12-HSL 40 20 0 TA isolates ID isolates