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Figure 3

Palmitoyl CoA. +. PL-D. Cannabinoids. SPT. Ketosphinganine. PL-A2. Membrane lipid precursors. Lyso-PL. LPA. 3KSR. Sphinganine. Lyso-Phosphatidyl choline. PAF. CerS. *. Phosphatidyl choline. +. Dihydroceramide. 1,2 DAG. Phosphatidyl choline. DHD. SMS. Sphingomyelin.

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  1. Palmitoyl CoA + PL-D Cannabinoids SPT Ketosphinganine PL-A2 Membrane lipid precursors Lyso-PL LPA 3KSR Sphinganine Lyso-Phosphatidyl choline PAF CerS * Phosphatidyl choline + Dihydroceramide 1,2 DAG Phosphatidyl choline DHD SMS Sphingomyelin Ceramide SMase CDP-choline PL-B 2 fatty acids PCT CerS CDase 1,2 DAG Phosphocholine Sphingosine glycero phosphocholine CTP S1PP SK Choline (extracellular) Sphingosine 1-phosphate SPL Hexadecenal Ethanolamine Figure 3

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