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Founders

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Founders

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  1. Founders With the support of

  2. Selection process 40 15 10

  3. Selected Projects Comparison of bioassay, Scrapie Cell-Assay and ProteinMisfolding Cycle Assay performances for detection of endogenous Prion in sheepblood Principal Investigator: O. Andreoletti(INRA-ENVT, Toulouse, France)

  4. Selected Projects Probing the chemistry and conformational change underlyingautocatalytic self-propagation of misfolded prion protein Principal Investigator: M. Beekes(Robert Koch Institute, Berlin, Germany)

  5. Selected Projects Optimisation, evaluation and validation of a PMCA-based confirmatory screening assay to detect prions in human blood. A French and British Collaborative Study Principal Investigators: J. Coste (EFS-PM, Montpellier, France) M. Jones (SNBTS, Edinburgh, UK)

  6. Selected Projects Assessment of prion infectivity in blood in primate and sheep models, and evaluation of removal processes (extension 2009) Principal Investigator: D. Dernis (EFS-Nord, Lille, France)

  7. Selected Projects Infectivitytitrations of blood components fromchimpanzeesinfectedwith the agent of Gerstmann-Sträussler-Scheinker Syndrome in mice and comparison of sensitivity of mouse bioassays Principal Investigator: L. Gregori(FDA, USA)

  8. Selected Projects Evaluation of cold atmospheric plasma to decontaminatesurgical instrument surfaces and eliminate prion infectivity Principal Investigators: C. W. Keevil(Southampton University, UK) R. Hervé (Southampton University, UK)

  9. Selected Projects An assessment of the relevancy of sheep and mice animal model for bloodsafety investigation Principal Investigator: C. Lacroux(INRA-ENVT, Toulouse, France)

  10. Selected Projects Detection of PrPSc (a biomarker for TSE infection) in bloodusing QUIC shaketechnology: validation of in vitro studieswithinfectivitymodels Principal Investigators: J. C. Manson(The Roslin Institute, UK) S. MacCutcheon(The Roslin Institute, UK)

  11. Selected Projects Elucidation of the misfoldingprocess… Insights into a preamyloid state by selectivelytrapping prion proteins in oligomericforms Principal Investigator: J. Torrent (INSERM, Montpellier, France)

  12. Selected Projects Riskassessment of Insoluble PrPfrom normal humanbrains Principal Investigator: W.Q. Zou (Case Western Reserve University, Cleveland, USA)