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Study on the impact of Zyflamend on cell growth in hamster cheek pouch carcinogenesis, with BrdU-labeling index analysis. Results show significant inhibition of cell proliferation compared to DMBA-treated group.
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Supplemental data Table 1. Effects of topical Zyflamend on cell proliferation (BrdU-labeling index*) of DMBA-induced oral carcinogenesis in hamster cheek pouch Experiment 2 *BrdU-labeling index (%) is calculated based on the number of positively staining cells by number of epithelial cells in a defined control area. For each case, 4~6 high-power fields (x400) were randomly picked out to count more than 1,000 epithelial cells.**p<0.01 compared to positive control (DMBA-treated group)
Table 2. Inhibition of cell proliferation by Zyflamend and its components in RBL-1 cells