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Objectives

NSF-CRCD Chemicals from Biorenewables PI: Charles E. Glatz co-PIs: Surya Mallapragada Balaji Narasimhan Peter Reilly Jacqueline Shanks. Objectives.

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Objectives

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  1. NSF-CRCD Chemicals from BiorenewablesPI: Charles E. Glatz co-PIs: Surya Mallapragada Balaji Narasimhan Peter Reilly Jacqueline Shanks

  2. Objectives • Develop four 1-credit open-ended multidisciplinary laboratory courses involving “Chemicals from Biorenewables” to be integrated with existing and new bioengineering-related ChE classes • Target audience: • undergraduate (seniors) and graduate students in Chemical Engineering • undergraduate and graduate students in Biochemistry and Biophysics.

  3. Motivation: Research • ChE evolving from a petrochemical-based to a biorenewables-based discipline Product Species used Company Indigo Microbial Genencor (Poly)lactic acid Microbial Cargill/Dow Biopol Microbial/plants Monsanto 1,3 propane diol Microbial DuPont

  4. Motivation: Research • “Although classical chemical engineering and the material sciences will remain extremely important well into the future, it will be difficult, if not impossible, to maintain the benefits of developed economies and extend them to developing countries in a sustainable manner without employing biotechnology". [DuPont website] • Current ChE curriculum does not reflect this trend • Introduce new courses to cover this new technology

  5. Motivation: Educational • Problem-based learning • Open-ended problems • Learning based approach • Students direct learning of the topic • Problems provide motivation for learning • Interdisciplinary • Team-based approach • ABET criteria • Life-long learning

  6. Existing Programs/ Resources • Research of the PIs • Size of the department - among top 10 ChE programs in the country • Emphasis on quality undergraduate education • Plant Sciences Institute • New faculty hire • Project LEARN • Bioethics Institute

  7. Proposed Curriculum Structure • Four new 1-credit laboratories - each associated with an existing or new ChE 400 or 500 level biotechnology related theory course • Each laboratory course has one open-ended design project topic and list of desired outcomes • Students work in teams of three - each team will have students with a biology/biochemistry background • Opportunity for problem-based, student-directed, multidisciplinary team-based learning • Bioethics component

  8. Proposed Curriculum Structure Investigator Research Instruction P. Reilly Protein Engineering Biochemical Engr (425) J. Shanks Plant Metabolic Engineering Metabolic Engr (new) S. Mallapragada Materials for Tissue Culture Biomaterials (595G) B. Narasimhan Polymeric Materials Polymers (443) C. Glatz (PI) Bioseparations Bioseparations (562) R. Seagrave Models of Biosystems Biomed Engr (540), Assessment

  9. Proposed Laboratory Modules • Bioinformatics • Metabolic engineering • Plant protein recovery • Development of materials for skin tissue propagation

  10. Impact • Make ChE education more relevant for our undergraduate students • Teach students • problem-based learning techniques • develop their metacognitive abilities • life-long learning • Coupling these educational techiques with valued new technologies • Integrate some of these new experiments in a non open-ended manner into the required ChE undergraduate laboratories

  11. Potential Collaborators • Biochemistry and Biophysics Department • Food Science and Human Nutrition • Industrial collaborators • Advanced Tissue Sciences • Cargill • Dow Agrosciences • Genencor • Ajinomoto • Amersham Pharmacia • Prodigene

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