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A. A. 4. Reporter: coll-73-luc +NLSA. 3.5. 3. 2.5. Relative luciferase value. 2. 1.5. 1. 0.5. 0. NH. E2. DES. PPT. Estren. OHT. Ral. Idox. Nafox. ICI. E2+ICI. B. 3.5. Reporter: coll-73-luc + ER  148-530 Flag. 3. 2.5. Relative luciferase value. 2. 1.5. 1. 0.5.

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  1. A A 4 Reporter: coll-73-luc +NLSA 3.5 3 2.5 Relative luciferase value 2 1.5 1 0.5 0 NH E2 DES PPT Estren OHT Ral Idox Nafox ICI E2+ICI B 3.5 Reporter: coll-73-luc + ER 148-530 Flag 3 2.5 Relative luciferase value 2 1.5 1 0.5 0 NH E2 DES PPT Estren OHT Ral Idox Nafox ICI E2+ OHT E2+ ICI C 3 Reporter: TRE-tk-luc NH 2.5 E2 2 OHT Relative luciferase value 1.5 ICI 1 0.5 0 NLSA ER 148-530 Flag D 3 Reporter: coll-73-luc + ER wt + ER wt 2.5 2 Relative luciferase value 1.5 1 0.5 0 NH Ral NH E2 PPT ICI E2 Ral ICI DES OHT Idox DES PPT Idox Nafox OHT Nafox Estren Estren

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