'Pre mrna' diaporamas de présentation

Chapter 13: RNA Processing and Post-Transcriptional Gene Regulation

Chapter 13: RNA Processing and Post-Transcriptional Gene Regulation. The discovery of split genes along with some other findings of recent years, shows that the genetic apparatus of the cell is more complex, more variable, and more dynamic than any of us had suspected.

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RNA SPLICING AND PROCESSING CHAPTER 21 ( GENES X )

RNA SPLICING AND PROCESSING CHAPTER 21 ( GENES X ). Introduction to RNA processing. Transcription elongation is tightly coupled to RNA processing. Eukaryotic mRNAs are modified at their beginning, middle and end. Why modify mRNA? Assess if mRNA is intact

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Molecular Biology Primer

Molecular Biology Primer. Angela Brooks, Raymond Brown, Calvin Chen, Mike Daly, Hoa Dinh, Erinn Hama, Robert Hinman, Julio Ng, Michael Sneddon, Hoa Troung, Jerry Wang, Che Fung Yung. Section1: What is Life made of?. Outline For Section 1:. All living things are made of Cells

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Chapter 15 : Post-transcriptional events II: Capping and polyadenylation

Chapter 15 : Post-transcriptional events II: Capping and polyadenylation. Cap structure. Sequence of events in capping. a. a phosphohydrolysis removes the terminal phosphate from a pre-mRNA; b . a guanylyl transferase adds the capping GMP.

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Chapter 17

Chapter 17. From Gene to Protein. Overview: The Flow of Genetic Information. The information content of DNA is in the form of specific sequences of nucleotides along the DNA strands The DNA inherited by an organism leads to specific traits by dictating the synthesis of proteins

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11.1 Genes are made of DNA

11.1 Genes are made of DNA. Griffith Experiment. Avery Experiment. -Destroyed proteins -Mice still died with mix. Hershey Chase Experiement. Virus- nucleic acid wrapped in protein; needs host to reproduce Bacteriophage- virus that infects bacteria. Hershey Chase Experiment. Question 1 & 2.

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Gene Expression in Eukaryotes

Gene Expression in Eukaryotes. mRNA Transcription and Processing. Eukaryotic Transcription Machinery. RNA polymerase II synthesizes all eukaryotic mRNA precursors composed of 12 different subunits remarkably conserved from yeast to mammals Polymerase II promoters

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14.1 Many Genes Have Complex Structures

14.1 Many Genes Have Complex Structures. Gene Organization. The concept of colinearity and noncolinearity. Gene Organization. Introns Regions of RNA that are not reflected in protein sequence INTervening sequences Exons Regions of RNA that are reflected in protein sequence

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V5: mRNA translation

V5: mRNA translation. The brief existence of an mRNA molecule begins with transcription and ultimately ends in degradation. During its life, an mRNA molecule may also be processed, edited, and transported prior to translation.

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Chapter 17

Chapter 17. I. The connection between genes and proteins A. Garrod, British physician - 1909 1. Hypothesis: 2. Studied Alkaptonuria a. urine appears black because it contains alkapton b. people with disease lack enzyme to break down alkapton

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RNA Processing

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Systematic identification of abundand A-to-I editing sites in the human transcriptome

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Received for publication, January 24, 2003, and in revised form, April 29, 2003

Serine-Arginine-rich Protein p30 Directs Alternative Splicing of Glucocorticoid Receptor Pre-mRNA to Glucocorticoid Receptor ? in Neutrophils*. Received for publication, January 24, 2003, and in revised form, April 29, 2003

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Molecular Biology Primer for CS and engineering students

Molecular Biology Primer for CS and engineering students. Alan Qi January, 2010. CS69000 Advanced Bioinformatics.

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An extensive network of coupling among gene expression machines - Review

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The role of pre-mRNA secondary structure in gene splicing

The role of pre-mRNA secondary structure in gene splicing. Sanja Rogic Computer Science Department, UBC. Gene splicing. Splice sites consensus sequences. consensus sequences are necessary but not sufficient for splicing. R = purines (A, G) Y = pyrimidines (C, U). Motivation.

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Chapter 14 RNA Processing I : Splicing

Chapter 14 RNA Processing I : Splicing. Summary of splicing Transcription Primary transcript ? splicing mature transcript. Evidences for introns R-loop in the electron microsopic view of chromatin sequencing ; compare genomic DNA and cDNA. Splicing signals and mechanism.

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M4-25D

U1-2’- O- Me. +. +. +. +. M4-25D. bcl-x S lariats. bcl-x L lariats. pre-mRNA. 1 2 3 4 5 6 7 8. xL /xS 6.3 2.0 2.3 0.8 0.7 2.9 1.0 2.7.

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