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Nerve conduction

Nerve conduction

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Nerve conduction

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  1. Nerve conduction Sompol Tapechum M.D., Ph.D. Department of Physiology Faculty of Medicine Siriraj Hospital

  2. Objectives • นักศึกษาสามารถบอกประโยชน์ของการวัด nerve conduction velocity ได้ • นักศึกษาสามารถบอกวิธีการวัด nerve conduction velocity ได้ • นักศึกษาสามารถบอกปัจจัยที่มีผลต่อ nerve conduction velocity ของ axon ได้

  3. Nervous system

  4. Structure of Nervous system • Central nervous system (CNS) • Brain • Cerebrum • Cerebellum • Brainstem • Spinal cord • Peripheral nervous system (PNS) • Nerves • Cranial nerve 12 pairs • Spinal nerve 31 pairs

  5. Spinal nerve and Cranial nerve

  6. Nerve structure • Nerve = Bundle of axon • Component of nerve • Motor • Somatic • Autonomic • Sensory • Somatic • Visceral

  7. Axon Orthodromic Motor neurons Antidromic Sensory neurons Orthodromic Antidromic

  8. Types of axon

  9. Type of axon

  10. Nerve conduction

  11. Sensory conduction study • Antidromic

  12. Sensory conduction study • Orthodromic

  13. Motor conduction study • Orthodromic

  14. Median nerve

  15. Motor conduction study:Median nerve

  16. Motor neuron Neuromuscular junction

  17. Neuromuscular junction

  18. D1-D2 NCV = L1-L2 Nerve conduction velocity D2 D1 Latency (s) L1 L2

  19. Sensory conduction study:Median nerve

  20. Purposes of Nerve conduction study • To diagnose nerve damage or destruction • To follow up nerve regeneration after damage • To evaluate diseases of nerve or muscle

  21. Normal nerve conduction velocity • normal conduction velocity • approximately 50 to 60 meters per second. • may vary from one individual to another and from one nerve to another.

  22. Carpal tunnel syndrome

  23. Nerve injury

  24. Axon regeneration 2-4 mm/day

  25. Myasthenia gravis