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This study investigates how ERK2 modulates interactions between Apaf-1, p53, and Pro-casp8, providing insights into apoptotic signaling pathways. The findings shed light on the specificity of these interactions and their impact on cell fate decisions.
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wt apaf-1-/- p53-/- Pro-casp8 p48 unspecific band ERK2 TPT (h) C 8 24 C 8 24 C 8 24 Supplemental Figure 2