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This study explores the relationship between Mrp4 and Bsep mRNA levels in rat liver cells and their effect on hepatic transporters. Results show significant findings with p<0.05, suggesting implications for liver function regulation.
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A B 350 35 p<0.05 300 30 250 25 Mrp4 mRNA (AU) Bsep mRNA (AU) 200 20 150 15 100 10 50 5 0 0 0 36 48 72 h 0 36 48 72 h +/+ -/- +/+ -/- Mrp3 Mrp3 Mrp3 Mrp3 Supplementary Fig. 6