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GFP-ER a

--. --. --. --. LMB. ALLN. ALLN. ALLN. ALLN. LMB. LMB. LMB. A. B. GFP-ER a. proteasome. merged. Nu. a. b. c. vehicle. f. e. d. E2. Cyt. +E2. 500 nm. 100 nm. C. D. E2. ICI. RU58. GFP-ER a. proteasome. merged. vehicle. c. a. b.

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GFP-ER a

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  1. -- -- -- -- LMB ALLN ALLN ALLN ALLN LMB LMB LMB A B GFP-ERa proteasome merged Nu a b c vehicle f e d E2 Cyt +E2 500 nm 100 nm C D E2 ICI RU58 GFP-ERa proteasome merged vehicle c a b 1 2 3 4 5 6 7 8 9 10 11 12 GFP-ERa ICI * ERa e d f GAPDH ICI + ALLN * - unspecific band h g i RU58 Relative ERa fold induction j k l RU58 + ALLN EtOH EtOH E2 ICI RU58 E2 ICI RU58 GFP-ERa ERa

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