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Bacterial Meningitis. By: Lauren Powell. What is Bacterial Meningitis?. Inflammation of the meninges ihttp ://en.wikipedia.org/wiki/Meningitis. (http://www.cdc.gov/meningitis/about/causes.html). What bacteria(s) cause it?. http :// www.cdc.gov/meningitis/about/causes.html.
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Bacterial Meningitis By: Lauren Powell
What is Bacterial Meningitis? • Inflammation of the meninges ihttp://en.wikipedia.org/wiki/Meningitis
(http://www.cdc.gov/meningitis/about/causes.html) What bacteria(s) cause it? http://www.cdc.gov/meningitis/about/causes.html
Neisseriameningitidis • Anti-phagocyticpolysaccharide capsule • Surface proteins http://www.textbookofbacteriology.net/neisseria.html
How N. meningitidisenters the meninges http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830671/?tool=pubmed
Is bacterial meningitis contagious? • Spread by respiratory or throat secretions Http://www.cdc.gov/meningitis/about/faq.html Image: www.ewu.edu/x52254.xml
People at High Risk • Children under 5 • Living in close contact • Immunocompromised • Severe head trauma or chronicinfection https://www1.qiagen.com/GeneGlobe/PathwayView.aspx?pathwayID=50 http://www.cdc.gov/meningitis/about/risk-factors.html Image:www.kuyper.edu/StudentLife/housing.aspx
Symptoms • Fever, headache, stiff neck • Infants: inactivity, vomiting, irritability, poor feeding http://www.cdc.gov/meningitis/about/faq.html Image: http://www.abpischools.org.uk/res/coResourceImport/resources04/diseases/images/meningitis.jpg
How to Diagnose? • Grow bacteria from cerebrospinal fluid • spinal tap http://www.cdc.gov/meningitis/about/faq.html Image: http://adventures.worldnomads.com/uploadimages/spinaltap-banner.jpg
Treatment • Antibiotics • Cephalosporins, Penicillin-type antibiotics, & Aminoglycoside drugs • Corticosteroids • Prophylaxis • Rifampin, Cipro, & Rocephin http://www.everydayhealth.com/meningitis/using-antibiotics-to-treat-meningitis.aspx http://kidshealth.org/parent/infections/lung/meningitis.html# Imagedic.academic.ru/dic.nsf/ruwiki/1030251
Resistance • THREAT! • Certain strains resistant to penicillin http://www.everydayhealth.com/meningitis/using-antibiotics-to-treat-meningitis.aspx Image: http://itech.dickinson.edu/chemistry/?cat=65
Complications • Hearing loss, learning disability, paralysis • Severe cases: brain damage, coma, or death http://www.dhpe.org/infect/Bacmeningitis.html image: wwwsodahead.com/.../question-781593/
Prevention • Routine Immunization • Good hygiene http://kidshealth.org/parent/infections/lung/meningitis.html# Image: http://www.tulsa-health.org/media/images/Bacterial%20Men%20Table.gif
Developed vs. Developing Countries • Developed • 3 per 100,000 annually • Developing • Epidemics • Sub-Saharan Africa: 500 per 100,000 annually http://en.wikipedia.org/wiki/Meningitis
♦ "Meningitis belt" ♦ epidemic zones ♦ sporadic cases http://en.wikipedia.org/wiki/Meningitis
Public Health Response (WHO) • Epidemic Preparedness • Epidemic Response http://www.who.int/mediacentre/factsheets/fs141/en/ Image:www.msf.org.uk/meningitis.focus
Bibliography • http://www.faqs.org/health/topics/59/Antibiotics.html • http://findarticles.com/p/articles/mi_m1370/is_n7_v25/ai_11348636/ • http://en.wikipedia.org/wiki/Haemophilus_influenzae • http://www.cdc.gov/meningitis/global.html • http://www.ct.gov/dph/cwp/view.asp?a=3136&q=388352 • http://www.infoplease.com/ipa/A0903696.html