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Impact of Pacing on Cardiac Function: A Steady-State Analysis

This study explores the effects of pacing on various cardiac parameters under steady state conditions. By analyzing dP/dtmax, left ventricular pressures, and oxygen consumption indices, we assess the implications of intrinsic versus paced strategies in cardiac performance. Data compiled from Kass et al. (1999) and Nelson et al. (2000) inform this comprehensive review, providing critical insights into pacing location and its impact on left ventricular function and myocardial oxygen demand. Our findings aim to contribute valuable knowledge to cardiac pacing strategies and their clinical applications.

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Impact of Pacing on Cardiac Function: A Steady-State Analysis

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  1. Pacing ON Pacing OFF 2 min Steady State 1112.0 1193.0 dP/dtmax -727.0 -841.0 114.4 114.0 AOP 50.8 54.7 113.5 113.0 LVP 1.0 0.4 1151.0 1151.0 ECG 865.0 870.0 0.0 2.5 5.0 7.5 10.0 0.0 2.8 5.6 8.4 11.2 TIME (s) TIME (s) (Kass et al, Circulation 1999, 99:1567)

  2. МЖП 120 120 80 80 40 40 0 0 0 100 200 300 0 100 200 300 120 120 80 80 40 40 0 0 0 100 200 300 0 100 200 300 Место стимуляции ПЖ (Kass et al, Circulation 1999, 99:1567) Верхушка ПЖ Intrinsic Paced Давление ЛЖ (mm Hg) Свободная стенка ЛЖ Бивентрикулярная ЭКС Давление ЛЖ (mm Hg) Объём ЛЖ(mL) Объём ЛЖ(mL)

  3. Nelson et al Circulation 2000;102: 3053-3059 LV Pacing 26 Dobutamine 24 22 20 Миокардиальный индекс потребления кислорода 18 16 14 12 600 700 800 900 1000 500 Исходный dP/dtmax (mmHg/s)

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