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The innovative stepwise process of generating induced multipotent progenitor cells (iMPC-Hep) is critical for advancing hepatocyte transplantation. According to Forbes and Alison (2014), this method represents a significant breakthrough in regenerative medicine. The careful development of iMPC-Hep may enhance transplantation outcomes, providing a sustainable source of liver cells and addressing the shortage of donor organs. This research highlights the potential for iMPC-Hep to transform liver disease treatment, paving the way for more effective therapies.
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Figure 1 Stepwise iMPC-Hep generation Forbes, S. J. & Alison, M. R. (2014) Knocking on the door to successful hepatocyte transplantation Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2014.44