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This supplemental figure illustrates the experimental outcomes of combining Vismodegib with various chemotherapeutic agents, including 5-fluorouracil and cisplatin, on AGS and MKN-45 gastric cancer spheroids. The analysis aims to elucidate the synergistic effects of these treatments and their implications for improving therapeutic strategies in gastric cancer. Visual data representations are provided to show cell viability, growth patterns, and interactions in response to the treatments.
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Yoon et al. Supplemental Figure S3 A AGS MKN-45 N87 Vismodegib B 5-fluoruracil DMSO Vismodegib 5-fluoruracil Cisplatin Cisplatin AGS Spheroid MKN-45 Spheroid N87 Spheroid